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Nurse practitioner salary in Mississippi (2026)

The average nurse practitioner salary in Mississippi is $125,340 per year. A small pool of very high earners pulls that average upward, so the median of $124,730 gives employers a more reliable starting point for most hiring decisions. Mississippi employs 4,690 nurse practitioners, and the $610 gap between the mean and median signals real variation in the candidate pool you will be evaluating. Junior nurse practitioners in Mississippi typically earn around $98,780, while senior specialists reach and exceed the $156,830 level at the 90th percentile. Plan for a range rather than a single number when budgeting for a nurse practitioner hire in Mississippi, and anchor that range to the seniority and specialization of the role you are filling.

Metric / Value

Metric

Value

Median Annual Salary

$124,730

Average Annual Salary

$125,340

vs. National Average

8.7% below the national mean of $137,300

Data comes from the and covers 4,690 employed nurse practitioners across Mississippi.

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Nurse practitioner salary percentiles in Mississippi

Percentile

Annual Salary

10th Percentile

$98,780

25th Percentile

$106,660

75th Percentile

$134,020

90th Percentile

$156,830

Employers hiring at the entry level can anchor offers near $98,780, while roles requiring advanced specialization or significant experience will need to approach or exceed $156,830 to attract qualified candidates. The $58,050 spread across the full range reflects how much seniority and specialty focus move compensation for nurse practitioners in Mississippi.

Nurse practitioner salary by city in Mississippi

City

Average Annual Salary

Gulfport

$129,270

Jackson

$126,930

Meridian

$121,660

Hattiesburg

$119,160

Where you hire within Mississippi will affect your compensation budget in a meaningful way. Gulfport carries the highest average at $129,270, while Hattiesburg sits at $119,160, a difference of $10,110 that can shift your annual payroll cost noticeably when hiring multiple nurse practitioners. Employers with flexibility on location may find Hattiesburg or Meridian offer a lower-cost entry point without moving far from the statewide norm.

How Mississippi compares to other states

State

Average Annual Salary

Median Annual Salary

Mississippi

$125,340

$124,730

Arkansas

$130,260

$125,660

Georgia

$128,800

$129,430

Louisiana

$126,630

$125,600

Tennessee

$115,510

$117,590

Alabama

$110,970

$105,750

Mississippi sits in the middle of the regional peer group, making it a moderately priced market for nurse practitioner hiring compared to neighboring states. Arkansas leads the group at $130,260 mean and Louisiana follows closely at $126,630, both above Mississippi's $125,340. Tennessee and Alabama come in below Mississippi, so employers in those states face lower compensation expectations while employers recruiting across state lines from Arkansas or Georgia will need to match higher benchmarks.

Frequently asked questions about nurse practitioner salary in Mississippi

Mississippi's mean nurse practitioner salary of $125,340 places it in the middle of its regional peer group. Arkansas ($130,260) and Georgia ($128,800) both pay more on average, while Tennessee ($115,510) and Alabama ($110,970) pay less. If you are competing for candidates who have offers from Arkansas or Georgia, plan to close that gap with non-salary benefits or other incentives.

Nurse practitioners at the 90th percentile in Mississippi earn $156,830 per year. If you are hiring a senior specialist or a candidate with a highly sought-after subspecialty, budget at or above that threshold to remain competitive. Candidates at that level typically have significant clinical experience and may hold leadership or supervisory responsibilities.

The published salary range for nurse practitioners in Mississippi runs from $98,780 at the 10th percentile to $156,830 at the 90th percentile. Entry-level or newly licensed practitioners will generally fall toward the lower end, while those with specialized training or years of experience will command figures closer to the top. Use the 25th percentile of $106,660 and the 75th percentile of $134,020 as practical guardrails when setting a range for a mid-career hire.

The average nurse practitioner salary in Mississippi is $125,340 per year, with a median of $124,730. The close alignment between the mean and median tells you the market is relatively stable without extreme outliers distorting the picture. For most hiring decisions, anchoring your initial offer near the median of $124,730 and adjusting upward for experience or specialization is a practical approach.

Nurse Practitioner salary by state

Data sourced from the , 2025, SOC code 29-1171 (Nurse Practitioners).

Disclaimer

Rippling and its affiliates do not provide tax, accounting, or legal advice. This material has been prepared for informational purposes only, and is not intended to provide or be relied on for tax, accounting, or legal advice. You should consult your own tax, accounting, and legal advisors before engaging in any related activities or transactions.

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Nurse practitioner salary in Louisiana (2026)

Louisiana nurse practitioners earn $126,630 on average. See salary percentiles, city breakdowns, and how Louisiana compares to neighboring states.

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Nurse practitioner salary in Alabama (2026)

Nurse practitioner salaries in Alabama average $110,970, with pay ranging from $86,300 to $134,650. See how Alabama compares to neighboring states.

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Nurse practitioner salary in Arkansas (2026)

Nurse practitioner salaries in Arkansas range from $99,420 to $205,810. See median pay, city breakdowns, and how Arkansas compares to neighboring states.

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Nurse practitioner salary in Tennessee (2026)

Tennessee nurse practitioners earn a median $117,590 annually. Compare salaries by city, percentile, and neighboring states to budget competitive offers.

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Nurse practitioner salary in Oklahoma (2026)

Nurse practitioner salaries in Oklahoma average $134,200, with pay ranging from $99,490 to $167,950. See city breakdowns and state comparisons.

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Registered nurse salary in Mississippi (2026)

Registered nurse salaries in Mississippi average $78,950, with pay ranging from $60,610 to $100,350. See city breakdowns and state comparisons to budget your next hire.

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Nurse practitioner salary in South Carolina (2026)

Nurse practitioner salaries in South Carolina average $124,170, ranging from $97,080 to $160,170. See BLS data by city, percentile, and neighboring state.

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Nurse practitioner salary in South Carolina (2026)

Nurse practitioner salaries in South Carolina average $124,170, ranging from $97,080 to $160,170. See BLS data by city, percentile, and neighboring state.

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